Dimitriadis et al., Eur J Endocrinol 2008
(Hyperthyroidism) :
In monocytes from the euthyroid subjects, IGF-I increased the abundance of GLUT3 and GLUT4 on the monocyte surface by 25 and 21 % respectively ( P < 0.0005 with repeated measures ANOVA )
Yu et al., Brain Res 2012
:
Moreover, IGF-1 stimulated HIF-1a and GLUT3 protein expression through phosphatidylinositol 3-kinase (PI3K)/Akt/mTOR dependent pathways