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Ye et al., Eur J Biochem 2000 (Choriocarcinoma...) : Taken together, it is concluded that okadaic acid induces the expression of p100 RasGAP protein in JEG-3 cells preceded by activation of ERK and AP-1 cascade, and that this okadaic acid induced p100 RasGAP expression is independent of protein kinase C-mediated pathway but requires c-Jun/AP-1 function
Christerson et al., J Cell Physiol 2002 : The reduced activation of AP-1 is dependent on the association of MEKK1 with p115 Rho GAP , because deletion of the Rho GAP SH3 domain, which abrogates their interaction, restores the stimulatory effect of MEKK1 on AP-1 activity