Gene interactions and pathways from curated databases and text-mining

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IRF1 — PTGS2

Text-mined interactions from Literome

Blanco et al., J Exp Med 2000 (Shock, Septic) : Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma dependent cyclooxygenase 2 expression
Rapizzi et al., Mol Pharmacol 2004 (Inflammation) : Consistent with a PAR dependent transcriptional activation, increases of iNOS and COX-2 transcripts were not caused by activation of transcription factors such as nuclear factor-kappaB, activator protein-1, signal transducer and activator of transcription-1 or interferon regulatory factor-1 , nor by mRNA stabilization