Gene interactions and pathways from curated databases and text-mining

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CRH — PTGS2

Text-mined interactions from Literome

Alvi et al., Immunology 1999 : The antibody to IL-1beta did not affect CRH stimulated or PAF stimulated PGE2 production or COX-2 expression
Markovic et al., J Clin Endocrinol Metab 2013 (Chorioamnionitis) : Objectives : In human myometrium we investigated cyclooxygenase 2 ( PGHS2 ) expression and regulation by CRH and the proinflammatory cytokine IL-1ß before and after labor ... Conclusions : CRH is involved in the inflammatory regulation of PGHS2 expression before and during labor ; these actions might be important in priming and preparing the myometrium for labor and cellular adaptive responses to inflammatory mediators