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CHGA — MAPK10
Text-mined interactions from Literome
Mahata et al., Neuroscience 1999
:
Expression of dominant negative ( inhibitory ) mutants of Sos, Ha-Ras, Rafl,
mitogen activated protein kinase , ribosomal protein S6 serine kinase II ( CREB kinase ) or CREB ( KCREB ) each
inhibited the nerve growth factor induced increase in
chromogranin A promoter activity
Tang et al., Mol Pharmacol 1998
(Adrenal Gland Neoplasms...) :
Chemical inhibition of either
MAPK or MAPK kinase
blocked the response of a transfected
chromogranin A promoter to nicotine or protein kinase C activation [ by phorbol-12-myristate-13-acetate ( PMA ) ], although nicotine evoked catecholamine secretion was unaffected ... Expression of the CREB antagonist KCREB blocked the
response of the
chromogranin A promoter to nicotine, cAMP, or
MAPK pathway activation by either chemical stimulation or cotransfection of active cascade components