Costessi et al., Bone 2005
:
In fact, by using the specific inhibitors SB203580 ( specific for p38 MAPK ) and PD98059 ( specific for ERK-1/2 MAPK ), we found that ERK-1/2, but not p38 , play a major role in Runx2 activation
Pei et al., Osteoarthritis Cartilage 2006
(Chondrosarcoma) :
Furthermore, IL-1beta induced the phosphorylation of Runx2 , and this effect was blocked by a p38 kinase inhibitor