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CD8A — TLR9
Text-mined interactions from Literome
Zhang et al., J Immunol 2010
(Diabetes Mellitus, Type 1...) :
The goal of this study was to determine the
effect of
TLR9 signaling on diabetogenic
CD8 ( + ) T cell activation and the course of type 1 diabetes ... We explored the
effects of CpG oligonucleotide, TLR9 antagonists, and genetic
TLR9 deficiency on the activation of diabetogenic
CD8 ( + ) T cells
Nadigel et al., Respir Res 2011
(Pulmonary Disease, Chronic Obstructive) :
CD8 ( + ) T cells exposed to CSC
increased TLR4 and
TLR9 levels and increased cytokine production
BĂ©land et al., PloS one 2012
(Inflammation) :
Both CpG/Poly ( I:C ) and autoreactive
CD8 ( + ) T cells
induced expression of
TLR9 and INF-? by the liver, and an up-regulation of homing and adhesion molecules CXCL9, CXCL10, CXCL16, ICAM-1 and VCAM-1
Heidegger et al., J Immunol 2013
(Salmonella Infections) :
We further show that this downregulation is dependent on TLR signaling, and that the
TLR activated naive
CD8 ( + ) T cells are blocked from entering GALT