Gene interactions and pathways from curated databases and text-mining

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CD8A — TLR9

Text-mined interactions from Literome

Zhang et al., J Immunol 2010 (Diabetes Mellitus, Type 1...) : The goal of this study was to determine the effect of TLR9 signaling on diabetogenic CD8 ( + ) T cell activation and the course of type 1 diabetes ... We explored the effects of CpG oligonucleotide, TLR9 antagonists, and genetic TLR9 deficiency on the activation of diabetogenic CD8 ( + ) T cells
Nadigel et al., Respir Res 2011 (Pulmonary Disease, Chronic Obstructive) : CD8 ( + ) T cells exposed to CSC increased TLR4 and TLR9 levels and increased cytokine production
BĂ©land et al., PloS one 2012 (Inflammation) : Both CpG/Poly ( I:C ) and autoreactive CD8 ( + ) T cells induced expression of TLR9 and INF-? by the liver, and an up-regulation of homing and adhesion molecules CXCL9, CXCL10, CXCL16, ICAM-1 and VCAM-1
Heidegger et al., J Immunol 2013 (Salmonella Infections) : We further show that this downregulation is dependent on TLR signaling, and that the TLR activated naive CD8 ( + ) T cells are blocked from entering GALT