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CD8A — ITGAX
Text-mined interactions from Literome
Bolinger et al., Blood 2008
:
Moreover, we could show that spontaneous activation of beta-gal-specific
CD8 ( + ) T cells in Tie2-LacZ mice was exclusively
dependent on
CD11c ( + ) dendritic cells (DCs), demonstrating that mhAgs presented by ECs remain immunologically ignored unless presentation by DCs is granted
Ling et al., J Immunol 2008
:
These data suggest that brain-resident
CD11c ( + ) cells
stimulate Ag-specific naive
CD8 ( + ) T cells locally in the CNS and may contribute to immune responses in the brain
Lindsay et al., J Immunol 2010
:
Taken together, these data demonstrate a critical
role for
CD11c ( + ) DCs for
CD8 responses but striking redundancy for innate cytokines and signaling by TLR and nucleotide binding oligomerization domain-like receptor pathways
Luckey et al., J Allergy Clin Immunol 2012
(Dermatitis, Allergic Contact) :
Subsequently, induction of tolerogenic
CD11c ( + ) DCs
leads to the generation of hapten-specific
CD8 ( + ) Treg cells, which protect against contact hypersensitivity