Gene interactions and pathways from curated databases and text-mining

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CD8A — ITGAX

Text-mined interactions from Literome

Bolinger et al., Blood 2008 : Moreover, we could show that spontaneous activation of beta-gal-specific CD8 ( + ) T cells in Tie2-LacZ mice was exclusively dependent on CD11c ( + ) dendritic cells (DCs), demonstrating that mhAgs presented by ECs remain immunologically ignored unless presentation by DCs is granted
Ling et al., J Immunol 2008 : These data suggest that brain-resident CD11c ( + ) cells stimulate Ag-specific naive CD8 ( + ) T cells locally in the CNS and may contribute to immune responses in the brain
Lindsay et al., J Immunol 2010 : Taken together, these data demonstrate a critical role for CD11c ( + ) DCs for CD8 responses but striking redundancy for innate cytokines and signaling by TLR and nucleotide binding oligomerization domain-like receptor pathways
Luckey et al., J Allergy Clin Immunol 2012 (Dermatitis, Allergic Contact) : Subsequently, induction of tolerogenic CD11c ( + ) DCs leads to the generation of hapten-specific CD8 ( + ) Treg cells, which protect against contact hypersensitivity