Gene interactions and pathways from curated databases and text-mining

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BMP2 — RUNX1

Text-mined interactions from Literome

Phimphilai et al., J Bone Miner Res 2006 : Conversely, RUNX2 expression synergistically stimulated BMP2 signaling in C3H10T1/2 cells
Komaki et al., J Cell Biochem 2007 : In contrast, BMP-2 increased runt related transcription factor ( Runx)-2, but failed to enhance alkaline phosphatase (ALP) and osteocalcin ( OCN ) gene expression in PDL cells
Naganawa et al., J Cell Biochem 2008 (MAP Kinase Signaling System) : Interestingly, BMP-2 induced nuclear accumulation of the runt related transcription factor ( Runx2 ) was markedly impaired in osteoblasts from Fgf2-/- mice ... Interestingly, BMP-2 induced nuclear accumulation of the runt related transcription factor ( Runx2 ) was markedly impaired in osteoblasts from Fgf2-/- mice
Chiou et al., Life Sci 2011 : Induction of differentiation by 8-PK was associated with increased bone morphogenetic protein (BMP)-2 expression, and sequentially up-regulated the phosphorylations of Smad1/5/8 and p38, and increased the nuclear translocation of runt related transcription factor 2 ( Runx2 )
Yoshioka et al., Eur J Immunol 2012 : Notably, BMP signalling controlled the phosphorylation of RUNX1 , revealing the molecular nature of its effect