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CD48 — IFNG

Text-mined interactions from Literome

Musgrave et al., J Interferon Cytokine Res 2003 : Induction of nonspecific CTL and interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) synthesis were impaired in the absence of CD2-CD48 interactions ... We conclude that CD2-CD48 interactions during T cell activation are critical for the synthesis of sufficient IL-2 and IFN-gamma to drive CD8 ( + ) T cells to differentiate into functional cytotoxic effector cells
Musgrave et al., Cell Immunol 2004 : CD2-CD48 interactions promote interleukin-2 and interferon-gamma synthesis by stabilizing cytokine mRNA
Lee et al., Blood 2006 (Calcium Signaling...) : In the absence of 2B4/CD48 interaction, NK cytotoxicity and IFN-gamma secretion on tumor target exposure is severely impaired