Gene interactions and pathways from curated databases and text-mining

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THPO — TYK2

Text-mined interactions from Literome

Ezumi et al., FEBS Lett 1995 : Thrombopoietin , c-Mpl ligand, induces tyrosine phosphorylation of Tyk2 , JAK2, and STAT3, and enhances agonists induced aggregation in platelets in vitro
Oda et al., Blood 1996 : To investigate the signaling processes induced by recombinant thrombopoietin, we used human platelets to recently show that thrombopoietin induces rapid tyrosine phosphorylation of Jak2, Tyk2 , Shc, Stat3, Stat5, and other proteins in human platelets
Miyakawa et al., Blood 1997 : To investigate the signaling processes induced by thrombopoietin, we have employed human platelets and recently demonstrated that thrombopoietin induces rapid tyrosine phosphorylation of Jak-2, Tyk2 , Shc, Stat3, Stat5, p120 ( c-cbl ) and other proteins in human platelets
Sattler et al., J Cell Physiol 1997 : We have previously shown that activation of c-MPL by thrombopoietin rapidly activates at least two cytoplasmic tyrosine kinases, JAK2 and TYK2 , after ligand binding