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MMP3 — PDGFB

Text-mined interactions from Literome

Kanaki et al., Biochem Biophys Res Commun 2002 : RT-PCR and Western blot analyses revealed that PDGF-BB induces MMP-3 expression in PAE cells that exclusively express either the PDGF-alphaR or the -betaR, but not in non transfected control cells ... LY294002, a PI3K inhibitor, reduced PDGF-BB stimulated MMP-3 expression in PAE cells expressing wild-type PDGF receptors ... In contrast, PDGF-BB induced MMP-3 expression in the presence of U-73122, a PLCgamma inhibitor
Laurent et al., FASEB J 2003 (Brain Neoplasms...) : We also show that the induction of MMP3 in cells expressing NOVH is potentiated by either cell density, serum, or PDGF-BB
Kordes et al., Pancreas 2005 (MAP Kinase Signaling System) : PDGF-BB increased PSC proliferation and migration, accompanied by elevated expression of matrix metalloproteinases (MMP)-13 and MMP-3
Karakiulakis et al., J Biol Chem 2007 (Anoxia) : PDGF-BB inhibited the synthesis and secretion of all hypoxia dependent MMP via Erk1/2 mitogen activated protein ( MAP ) kinase activation
Liu et al., Neurol Res 2008 (Disease Models, Animal...) : So, PDGF-B may induce the expression of MMP for the degradation of collagen type III on the wall of the saccular aneurysms