Gene interactions and pathways from curated databases and text-mining

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KCNH4 — PRKACG

Text-mined interactions from Literome

Ahi et al., Behav Brain Res 2004 : Inhibition of PKA impaired context- and tone dependent fear conditioning and significantly reduced the phosphorylation of Elk-1 , p90Rsk-1, Erk-1/2, and CREB
Keeley et al., Biotechniques 2005 (MAP Kinase Signaling System) : The novel hybrid transcription factor TetR-Elk-1 was regulated by MAPK ERK kinase 1 (MEK-1) overexpression, and TetR-CREB was regulated by protein kinase A (PKA) overexpression or elevation of cyclic AMP levels
Yao et al., J Biol Chem 1998 : Inhibition of PKA also reduced the ability of NGF and cAMP, but not EGF, to activate the transcription factor Elk-1 , reduced the induction of both immediate early and late genes after NGF treatment, and blocked the nuclear translocation of ERK1 induced by NGF