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GYS1 — NPY4R

Text-mined interactions from Literome

Browne et al., Biochem J 2001 (Diabetes Mellitus, Experimental) : Hepatic glycogen synthesis is impaired in insulin dependent diabetic rats owing to defective activation of glycogen synthase by glycogen bound protein phosphatase 1 (PP1)
González et al., Regul Pept 2005 : In rat hepatocytes, activation of PI3K/PKB, PKC and PP-1 mediates the GLP-1 induced stimulation of glycogen synthase
Kida et al., J Clin Invest 1992 (Insulin Resistance) : These results suggest that insulin activation of PP-1 could contribute to the stimulation of glycogen synthase by this hormone in human muscle
Turnbull et al., PLoS Genet 2011 (Disease Models, Animal...) : Polyglucosan formation is catalyzed by glycogen synthase , which is activated through dephosphorylation by glycogen associated protein phosphatase-1 (PP1)
Kelsall et al., J Neurochem 2011 (Astrocytoma...) : A key regulator of glycogen levels is glycogen targeted protein phosphatase 1 (PP1) , which dephosphorylates and activates glycogen synthase ( GS ) leading to an increase in glycogen synthesis
Henry et al., Arch Biochem Biophys 1993 : The roles of casein kinases I and II in the activation of protein phosphatase-1i (PP-1i) by glycogen synthase kinase-3 ( GSK-3 ) were studied using enzyme preparations from porcine heart
Brady et al., J Biol Chem 1998 : Cumulatively these results suggest that the weak activation of glycogen synthase in 3T3-L1 fibroblasts is mediated by GSK-3 inactivation, whereas in the more metabolically active adipocytes, the insulin-specific activation of glycogen synthase is mediated by PP1 activation