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EPB41 — RELA
Text-mined interactions from Literome
Bren et al., PloS one 2008
(Alstrom Syndrome) :
Finally, we demonstrate that the HIV protease cleavage of caspase 8 is necessary for optimal
NF-kappaB activation and that the HIV-1 protease specific cleavage fragment
Casp8p41 is
sufficient to stimulate HIV-1 replication through NF-kappaB dependent HIV-LTR activation both in vitro as well as in cells from HIV infected donors
Ma et al., Cancer Chemother Pharmacol 2009
(Breast Neoplasms) :
The objective of this study is to investigate the in vitro
effects of epoxypseudoisoeugenol-2-methyl butyrate (
EPB ), a phenylpropranoid isolated from Pimpinella corymbosa, on the activation of
NF-kappaB , cell growth, cell cycle progression and apoptosis in MCF-7 ( estrogen dependent ) and BT-549 ( estrogen independent ) breast cancer cells ...
EPB also
inhibited constitutive
NF-kappaB transcriptional activity in BT-549 cells
Taylor et al., AIDS 2010
(HIV Infections) :
We have previously shown that
Casp8p41 induced
NFkappaB activation enhances HIV LTR transcription and consequently increases HIV replication ... Herein, we questioned whether
Casp8p41 induced
NFkappaB activation impacts the cytokine profile of cells expressing Casp8p41