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CAT — TAT
Text-mined interactions from Literome
Kelly et al., Virology 1999
:
High levels of CAT activity were seen with HIV-LTR derived reporters that contained kappaB and TAR elements in
response to transfected
Tat in the absence of either transfected Rel A or exogenous TNF-alpha, and overexpression of IkappaBalpha with Tat inhibited
CAT activity by 60 % to 80 %, suggesting that some activation of NF-kappaB by Tat was occurring
Niyasom et al., Southeast Asian J Trop Med Public Health 2009
(Disease Progression...) :
Levels of
Tat dependent
chloramphenicol acetyltransferase (CAT) induced in HL3T1 cells with tat1 gene from HIV-1 isolates of high viral load group was significantly higher than those from low viral load group
Yu et al., Peptides 2012
(Body Weight...) :
PACAP-TAT decreased myeloperoxidase (MPO) activity,
increased catalase (CAT) activity and down-regulated interleukin 6 (IL-6) and malondialdehyde ( MDA ) levels in the lungs with a significantly higher efficiency than PACAP
Chuah et al., Hum Gene Ther 1994
:
Anti-TAR inhibited
Tat mediated HIV-1 LTR-driven
CAT reporter gene expression in a dose dependent fashion
Greenberg et al., Nucleic Acids Res 1997
:
Nevertheless, many of the inserted sequences exerted marked effects on
CAT gene expression and on
transactivation by
Tat at both the RNA and protein levels
Choudhury et al., J Acquir Immune Defic Syndr Hum Retrovirol 1998
:
Tat10-biotin inhibited tat gene induced expression of a stably transfected chloramphenicol acetyl transferase (CAT) reporter gene linked to the HIV-1 long terminal repeat ( LTR ) in a model cell assay, but did not
inhibit phorbol ester induced expression of
CAT , thereby demonstrating a Tat dependent mechanism of inhibition
Gibellini et al., J Immunol 1998
:
Moreover, the use of plasmids encoding for GAL4-CREB fusion proteins demonstrated that Tat induction of
pG4-CAT reporter gene required the CREB moiety of the GAL4-CREB fusion protein and that Ser133 CREB was
essential for
Tat activity