Gene interactions and pathways from curated databases and text-mining

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CAT — MMP1

Text-mined interactions from Literome

Zang et al., Int Immunopharmacol 2013 (Lymphoma, Large B-Cell, Diffuse...) : Phagocytosis, the loss of MMP , autophagy and the activated signaling pathways were all suppressed by ROS scavenger N-acetyl-l-cysteine (NAC), HO scavenger catalase or OH scavenger glutathione ( GSH )
Brenneisen et al., Free Radic Biol Med 1997 : The inhibition of catalase by aminotriazol ( ATZ ), inhibition of GSHPx by buthionine sulfoximine ( BSO ), and blocking the Fenton reaction by the iron chelator desferrioxamine ( DFO ) in concert led to an increase in steady-state MMP-1 mRNA levels, possibly dependent on intracellular H2O2 increase