Gene interactions and pathways from curated databases and text-mining

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IL1B — IL23A

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Kidoya et al., J Immunol 2005 (Inflammation) : IL-23 , which shares the p40 subunit with IL-12, but not IL-12 itself, induced IL-17 production synergistically with IL-1beta in resident PEC
Cho et al., J Immunol 2006 (Arthritis...) : IL-1beta further increased the production of IL-23 , which induced IL-17 production and OX40 expression in splenic CD4 ( + ) T cells of IL-1Ra ( -/- ) mice
Liu et al., Rheumatology (Oxford) 2007 (Arthritis, Rheumatoid) : To explore the source of the p19 subunit of interleukin-23 (IL-23) in joints with rheumatoid arthritis ( RA ), the effects of IL-1beta and tumour necrosis factor (TNF)-alpha on IL-23 gene expression in RA fibroblast-like synoviocytes and the effect of IL-23 on proinflammatory cytokines ... IL-1beta regulates IL-23 p19 expression via NF-kappaB and AP-1 pathways
Cheung et al., J Immunol 2008 (Inflammation) : IL-17A, IL-17F, and IL-23 could induce the release of chemokines GRO-alpha/CXCL1, IL-8/CXCL8, and MIP-1beta/CCL4 from eosinophils, while IL-17F and IL-23 could also increase the production of proinflammatory cytokines IL-1beta and IL-6
Goldberg et al., Mol Immunol 2009 (Arthritis, Rheumatoid...) : In contrast, IL-1beta mediated induction of IL-23 p19 expression was cell-specific ... Induction of IL-23 p19 expression by IL-1beta was present in FLS but almost absent in the DF derived from the same patients