Gene interactions and pathways from curated databases and text-mining

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HNF1A — UGT1A1

Text-mined interactions from Literome

Li et al., Drug Metab Dispos 2009 : Transcription of UDP-glucuronosyltransferase (UGT) 1A1 is regulated by the transcription factors, constitutive androstane receptor (CAR), pregnane X receptor (PXR), glucocorticoid receptor ( GR ), hepatocyte nuclear factor (HNF) 1 alpha , and HNF4 alpha
BĂ©langer et al., BMC molecular biology 2010 (Colonic Neoplasms) : Luciferase assays sustained a role for USF1/2 and HNF1-alpha in UGT1A1 regulation in colon cancer cells ... This study reveals that basal UGT1A1 expression in colon cells is positively regulated by HNF1-alpha and USF, and negatively regulated by DNA methylation