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PTGS2 — RARB

Text-mined interactions from Literome

Li et al., Oncogene 2002 (Esophageal Neoplasms) : The inhibitory effect of RAR-beta on COX-2 expression was further enhanced in the presence of RA, which was blocked by an RAR antagonist
Delage et al., Int J Cancer 2005 : HLD consumption induced early downregulation of PPARgamma ( -33.1 % ) and RARbeta ( -53.1 % ) mRNA expression concomitant with an increase in levels of COX-2 ( +45.5 % ) and beta-catenin ( +84.56 % ) and in the number of ACF ( 191.56 +/- 88.60 vs. 21.14 +/- 11.64, p < 0.05 )
Song et al., Oncogene 2005 : This study demonstrated that BPDE suppressed expression of RAR-beta ( 2 ) results in COX-2 induction and restoration of RAR-beta ( 2 ) expression reduces COX-2 protein in esophageal cancer cells, thereby further supporting our previous finding that RAR-beta ( 2 ) plays an important role in suppressing esophageal carcinogenesis