Gene interactions and pathways from curated databases and text-mining

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CD79A — TMED7

Text-mined interactions from Literome

Gesbert et al., J Biol Chem 2000 : We demonstrate that the decrease of p27 ( Kip1 ) is directly due to BCR/ABL in hematopoietic cells by two different approaches ... The PI3K inhibitor LY-294002 blocks the ability of BCR/ABL to induce p27 ( Kip1 ) down-regulation and inhibits BCR/ABL induced entry into S phase ... Overall, these data are consistent with a model in which BCR/ABL suppresses p27 ( Kip1 ) protein levels through PI3K/AKT, leading to accelerated entry into S phase
Banerji et al., Oncogene 2001 (Lymphoma, B-Cell...) : We show that BCR stimulation of WEHI 231 cells results in down-regulation of cyclin D2 and up-regulation of p27 ( Kip1 ), which are associated with pocket protein hypophosphorylation and E2F inactivation
Schuster et al., Blood 2003 : In contrast, the up-regulation of PU.1 and p27 ( Kip1 ) by G-CSF was not affected by Bcr-Abl
Craxton et al., Eur J Immunol 2007 : Likewise, BCR induced p27 ( Kip1 ) degradation was decreased in Bim KO compared to WT B cells
Richards et al., Eur J Immunol 2009 : BCR ligation leads to a more rapid decrease in p27 ( Kip1 ) levels in gp91(phox) KO B cells