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AKT2 — NOD1
Text-mined interactions from Literome
Zhao et al., Am J Physiol Endocrinol Metab 2011
(Insulin Resistance...) :
Furthermore,
NOD1 activation suppresses insulin signaling, as revealed by attenuated tyrosine phosphorylation and increased inhibitory serine phosphorylation, of IRS-1 and
attenuated phosphorylation of
Akt and downstream target GSK3a/3ß, resulting in decreased insulin induced glucose uptake in 3T3-L1 adipocytes
Zhou et al., Diabetes Metab 2012
(Insulin Resistance...) :
NOD1 activation weakened insulin signal transduction as revealed by increased JNK and IRS-1 Ser307 phosphorylation, inhibited IRS-1 tyrosine phosphorylation, and
reduced insulin induced phosphorylation of
Akt on Ser473 and Thr308 in human adipocytes