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DEAF1 — HTR1A

Pathways - manually collected, often from reviews:

• WikiPathways Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways: REST/DEAF1/HES5/HES1/CC2D1A → HTR1A (mim-transcription-translation)

Text-mined interactions from Literome

Lemonde et al., J Neurosci 2003 (Genetic Predisposition to Disease) : Stable expression of NUDR in raphe cells reduced levels of endogenous 5-HT1A protein and binding
Czesak et al., J Neurosci 2006 (Neuroblastoma) : However, in nonserotonergic cells that express 5-HT1A receptors ( septal SN48, neuroblastoma SKN-SH, and neuroblastoma/glioma NG108-15 cells ), Deaf-1 enhanced 5-HT1A promoter activity at the C ( -1019 ) -allele but not the G-allele, whereas Hes5 repressed in all cell types