Gene interactions and pathways from curated databases and text-mining

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ALOX5 — JUN

Text-mined interactions from Literome

Ghosh et al., Biochem Biophys Res Commun 2003 (Prostatic Neoplasms) : This report documents the fact that inhibition of arachidonate 5-lipoxygenase induces rapid activation of c-Jun N-terminal kinase (JNK) in human prostate cancer cells which is prevented by the 5-lipoxygenase metabolite, 5 ( S ) -HETE
Roumestan et al., Clin Exp Allergy 2008 : We then investigated whether these drugs affect NF-kappaB and AP-1 activities in A549 lung epithelial cells, and whether this potential regulation involves H1-receptor and 5-LO