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DSC2 — MAPK3

Text-mined interactions from Literome

Cui et al., Carcinogenesis 2012 (Lung Neoplasms...) : Furthermore, functional studies after stable transfection of a DSC3 expression vector showed that ectopic expression of DSC3 inhibited cell proliferation, anchorage independent growth, migration, as well as invasion, and most interestingly led to reduced phosphorylation levels of extracellular signal regulated kinase1/2
Pan et al., Biochim Biophys Acta 2013 : DSC concentration-dependently attenuated cell death, lactate dehydrogenase release, intracellular and mitochondrial ROS production, and d? collapse, modulated apoptosis related proteins ( Bcl-2, Bax, caspase-3, p53, and cleaved PARP ) expression, and inhibited phosphorylation of extracellular signal regulated kinase 1/2 in SH-SY5Y cells induced by HO
Liu et al., Eur J Pharmacol 2013 : Signal transduction studies indicated that DSC significantly inhibited LPS induced phosphorylation of Akt, but not c-Jun N-terminal kinase 1/2, p38, or extracellular signal regulated kinase 1/2