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MDM2 — MEFV

Text-mined interactions from Literome

Miwa et al., Biochem Biophys Res Commun 2006 (Carcinoma, Non-Small-Cell Lung...) : Soft-agar colony formation activity of p53-knockout MEF was increased by wild-type Mdm2 but not mutant Mdm2
Sashida et al., Mol Cell Biol 2009 (Cell Transformation, Neoplastic) : ELF4/MEF activates MDM2 expression and blocks oncogene induced p16 activation to promote transformation ... We found that Elf4/Mef activates Mdm2 expression ; thus, lack of or knockdown of Elf4/Mef reduces Mdm2 levels in mouse embryonic fibroblasts ( mef 's ), leading to enhanced p53 protein accumulation and p53 dependent senescence