Gene interactions and pathways from curated databases and text-mining

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NGF — PLAUR

Text-mined interactions from Literome

Chou et al., Brain Res Mol Brain Res 2000 : Wnt-1 decreased the NGF induced expression of the late-response gene SCG10 but not of the immediate early genes, fos, Nur77 and UPAR ( urokinase-type plasminogen activator receptor ) nor of the late-response genes GAP-43 and collagenase
Herschman et al., Neurochem Res 2000 (Adrenal Gland Neoplasms...) : Antisense oligonucleotide and anti-UPAR antibody experiments demonstrate that NGF induced UPAR expression is required for NGF-driven PC12 cell differentiation
Farias-Eisner et al., J Neurosci Res 2001 : UPAR and the secondary response genes collagenase-1 and transin are not induced in `` primed '' PC12 cells in response to NGF , and anti-UPAR antibody does not block morphological differentiation in these cells
Chen et al., Mol Endocrinol 2008 : NGF induced microarray expression of Plaur and Mmp10 genes was greatly enhanced in PC12-SH2B1beta cells, whereas NGF induced Plaur and Mmp3 expression was substantially depressed in PC12-SH2B1beta ( R555E ) cells ... NGF induced levels of uPAR and MMP3/10 and neurite outgrowth through Matrigel ( MMP3 dependent ) were also increased in PC12-SH2B1beta cells