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CRK — MMP1

Text-mined interactions from Literome

Xu et al., Biochem J 2001 : Partial inhibition of p38 MAPK activity resulted in the lowest level of MMP-1 expression, whereas total inhibition of p38 activity led to MMP-1 levels as high as in the absence of inhibitor ... Nuclear factor-kappaB (NF-kappaB), a previously identified positive regulator of MMP-1 expression induced by fl-coll [ Xu, Zutter, Santoro and Clark ( 1998 ) J. Cell Biol. 140, 709-719 ] was mediated by fl-coll activated p38alpha
Reunanen et al., J Biol Chem 2002 : Activation of endogenous or adenovirally expressed p38 alpha by adenovirally delivered constitutively active MKK3b and MKK6b also enhanced MMP-1 and MMP-3 expression and augmented the up-regulatory effect of ERK1/2 activation on the expression of these MMPs. Activation of ERK1/2 resulted in induction of c-jun, junB, and c-fos expression, whereas activation of p38 alone had no effect
Kim et al., J Lipid Res 2005 : We found that UV radiation increases MMP-1 expression and that this is mediated by p44 and p42 MAP kinase ( ERK ) and Jun-N-terminal kinase (JNK) activation but not by p38 activation
Pei et al., Osteoarthritis Cartilage 2006 (Chondrosarcoma) : Differential regulation of cytokine induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells : potential role of Runx2 in mediating p38 effects
Goda et al., Am J Pathol 2006 : However, the production of MMP-1 from CXCL12 stimulated NK cells was mediated by p38 and mitogen activated or extracellular signal-regulation protein kinase kinase 1/2 in a manner independent of the G ( i ) -coupled pathway
Oner et al., J Clin Endocrinol Metab 2008 (Chorioamnionitis...) : Our objective was to evaluate : 1 ) MMP-1 and MMP-3 expression in decidual sections from uncomplicated term, idiopathic preterm, and CAM complicated deliveries, and 2 ) the separate and interactive effects of IL-1beta, TNF-alpha, medroxyprogesterone acetate ( MPA ), and a p38 MAPK inhibitor ( SB203580 ) on MMP-1 and MMP-3 expression in term decidual cells (DCs)
Deraz et al., PloS one 2011 (Carcinoma, Squamous Cell...) : Interestingly, MMP-10 overexpression induced the decreased p38 activity and MMP-10 knockdown induced the increased p38 activity
Green et al., Journal of neuroinflammation 2013 (Tuberculosis) : Secretion and expression of MMP-1 and MMP-3 were both p38 dependent