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BCL10 — HGF
Text-mined interactions from Literome
Kosai et al., Hepatology 1999
(Death...) :
Moreover,
HGF strongly
induced Bcl-xL expression and blocked apoptotic signal transduction upstream of CPP32 ( caspase-3 ) in the liver, thereby leading to inhibition of massive hepatocyte apoptosis
Nomi et al., Biochem Biophys Res Commun 2000
(Liver Failure) :
Expression of
Bcl-xL and cyclooxygenase-2 (Cox-2) was
induced in liver by
HGF gene transfer
Nakamura et al., J Clin Invest 2000
(Disease Models, Animal...) :
HGF rapidly
augmented Bcl-xL expression in injured cardiomyocytes both in vitro and in vivo
Fornoni et al., Am J Pathol 2001
:
We investigated whether
Bcl-xL and Fas/Fas-ligand were regulated by CsA in cultured podocytes and whether CsA induced apoptosis was
prevented by
HGF or IGF-I ...
HGF , but not IGF-I, prevented apoptosis and
restored Bcl-xL levels ... The
regulation of
Bcl-xL by
HGF was mediated by the PI3'-K but not by the MEK-1 pathway
Cao et al., Am J Pathol 2009
(Mesothelioma) :
Up-regulation of
Bcl-xl by
hepatocyte growth factor in human mesothelioma cells involves ETS transcription factors
Kosai et al., Biochem Biophys Res Commun 1998
(Hepatic Encephalopathy) :
HGF strongly
induced Bcl-xL expression and subsequently blocked Fas mediated signaling pathway upstream of CPP32 in the liver