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CDK8 — EPHB2

Text-mined interactions from Literome

Wang et al., J Biol Chem 2002 : Mediator role of platelet derived growth factor and ERK
Alldridge et al., Exp Cell Res 2003 (MAP Kinase Signaling System) : Moreover, ANXA1 reduces proliferation by ERK mediated disruption of the actin cytoskeleton and ablation of cyclin D1 protein expression and not by ERK mediated induction of the cyclin dependent kinase , CDK2, inhibitor p21 ( cip/waf )
Zheng et al., J Neurosci Res 2009 : Surprisingly, BAPTA-AM did not block ERK activation, indicating that [ Ca ( 2+ ) ] ( i ) and Ras-Raf-MAPK are not coupled, and the activation of ERK alone is not sufficient to up-regulate Arc transcription
Panja et al., J Biol Chem 2009 : These results support a dominant role for ERK-MNK signaling in control of translational initiation and Arc synthesis during LTP consolidation in the dentate gyrus
Saito et al., J Exp Med 2010 (Cell Transformation, Neoplastic...) : In nonpolarized epithelial cells, Erk activation results in oncogenic stress, up-regulation of the p21 ( Waf1/Cip1 ) cyclin dependent kinase inhibitor, and induction of senescence
Hong et al., Exp Cell Res 2011 (Prostatic Neoplasms) : Ectopic expression of a constitutively active AR inhibited Raf/MEK/ERK mediated regulation of the differentiation markers, neuron-specific enolase and neutral endopeptidase, and the cyclin dependent kinase inhibitors, p16(INK4A) and p21 ( CIP1 ), but not Rb phosphorylation and E2F1 expression, indicating that AR has a specific role in the pathway mediated differentiation and growth inhibitory signaling
Kumar et al., J Biol Chem 2012 (Synaptic Transmission) : Mechanistically, intracellular mGluR5 mediated Arc induction is dependent upon extracellular and intracellular Ca ( 2+ ) and ERK1/2 as well as calmodulin dependent kinases as known chelators, inhibitors, and a dominant negative Ca ( 2+ ) /calmodulin dependent protein kinase II construct block Arc increases