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AQP5 — EPHB2

Text-mined interactions from Literome

Hoffert et al., J Biol Chem 2000 (MAP Kinase Signaling System) : This study demonstrates that AQP5 is induced by hypertonic stress and that induction requires activation of extracellular signal regulated kinase ( ERK ) ... ERK was selectively activated in MLE-15 cells by hypertonic stress, and inhibition of ERK activation with two distinct mitogen activated extracellular regulated kinase kinase ( MEK ) inhibitors, U0126 and PD98059, blocked AQP5 induction
Zhang et al., Am J Physiol Gastrointest Liver Physiol 2010 : In summary, the capsaicin induced secretory mechanism involved activation of TRPV1 and upregulation of AQP5 in an ERK dependent manner and promoted the redistribution of AQP5 in submandibular gland cells