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RELA — TLE1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: TLE1 — RELA Tetsuka et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: TLE1 — RELA (experimental interaction detection) Tetsuka et al., J Biol Chem 2000*
• IRef Bind_translation Interaction: TLE1 — RELA (coimmunoprecipitation) Tetsuka et al., J Biol Chem 2000*
• IRef Biogrid Interaction: TLE1 — RELA (physical association, affinity chromatography technology) Tetsuka et al., J Biol Chem 2000*
• IRef Ophid Interaction: TLE1 — RELA (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Ghosh et al., Biochem J 2007 : We have demonstrated using co-transfection assays that Sirt1 and TLE1 repress NF-kappaB activity ... Furthermore, analysis in Sirt1-null MEFs ( murine embryonic fibroblasts ) and HeLa cells stably expressing siRNA ( small interfering RNA ) specific to Sirt1 or TLE1 demonstrate that both Sirt1 and TLE1 are required for negative regulation of NF-kappaB activity
Joo et al., PloS one 2009 (Colitis...) : In vitro, TLE blocked LPS induced IkappaBalpha degradation, RelA translocation, NF-kappaB transcriptional activity and MIP-2 mRNA accumulation in IEC-18 cells