Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Segev et al., Proc Natl Acad Sci U S A 2002 : MIS induced NF-kappaB DNA binding activity and selectively up-regulated the immediate early gene IEX-1S in both androgen dependent and independent human prostate cancer cells in vitro
Ahn et al., J Dermatol Sci 2003 : In order to demonstrate the possible role of NF-kappaB activation on the synthesis of melanotrophic factors from the keratinocytes, the activities of NF-kappaB induced by melanogenic inhibitors (MIs) were determined in human HaCaT keratinocytes transfected with pNF-kappaB-SEAP-NPT plasmid
Hoshiya et al., Mol Cell Endocrinol 2003 (Breast Neoplasms...) : In both breast and prostate cancer cells, MIS activated NFkB DNA binding activity and induced IEX-1, an immediate early gene which regulates cell growth and apoptosis
Gupta et al., Cancer Res 2007 (Breast Neoplasms) : These results show a novel interaction between MIS stimulated Smad1 and NF-kappaB signaling in which enhancement of NF-kappaB DNA binding and gene expression by phospho-Smad1 is dependent on the sequence of the kappaB consensus site within the promoter