Lawson et al., Eur J Immunol 2010
:
While gain of Egr2 caused a decrease in Socs1 mRNA, loss of Egr2 resulted in downregulation of IL-7R, upregulation of Socs1 , and inhibition of Stat5 phosphorylation and IL-7 mediated survival post-selection
Stutz et al., Immunobiology 2012
(Toxoplasmosis, Animal) :
Indeed, induction of egr2 as well as SOCS1 was dependent on p38 MAP kinase and blockade of egr inhibited SOCS1 expression