Gene interactions and pathways from curated databases and text-mining

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SMAD3 — SOST

Text-mined interactions from Literome

van Bezooijen et al., J Exp Med 2004 (Bone Diseases, Developmental...) : In addition, sclerostin had no effect on BMP stimulated Smad phosphorylation and direct transcriptional activation of MSX-2 and BMP response element reporter constructs in KS483 cells
Nguyen et al., PloS one 2013 (Mechanotransduction, Cellular) : Furthermore, sensitivity to TGFß is required for the mechanosensitive regulation of Sclerostin , which is induced by TGFß in a Smad3 dependent manner