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PGF — RELA
Pathways - manually collected, often from reviews:
-
KEGG Pancreatic cancer:
NFKB1/RELA
→
FIGF/PGF/VEGFA/VEGFB/VEGFC
(gene expression, expression)
Text-mined interactions from Literome
Mandal et al., J Biol Chem 2005
(Inflammation) :
Most importantly, uteroglobin inhibits FP-mediated
NF-kappaB activation and cyclooxygenase-2 gene expression by binding and most likely by sequestering PGF2alpha into its central hydrophobic cavity, thereby
preventing FP-PGF2alpha interaction and suppressing the production of inflammatory lipid mediators
Taniguchi et al., Reproduction 2010
:
PGF ( 2a )
increased NFKB p65 protein expression in the nucleus of luteal cells 30 min after PGF ( 2a ) injection, and electrophoretic mobility shift assay revealed that PGF ( 2a ) increased binding activities of NFKB to the NFKB consensus sequence of the Ptgs2 gene promoter ... Simultaneous administration of both superoxide dismutase and catalase to scavenge reactive oxygen species ( ROS ) inhibited the increases of nuclear
NFKB p65 protein expression, lipid peroxide levels, and Ptgs2 mRNA expression
induced by
PGF ( 2a )