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HDAC4 — PPP2R2B
Text-mined interactions from Literome
Paroni et al., Mol Biol Cell 2008
:
PP2A regulates
HDAC4 nuclear import ... HDAC4 is dephosphorylated by PP2A and experiments using okadaic acid or RNA interference have revealed that
PP2A controls
HDAC4 nuclear import ... These observations suggest that
PP2A , via the dephosphorylation of multiple serines including the 14-3-3 binding sites and serine 298,
controls HDAC4 nuclear import
Li et al., Nat Med 2012
(Ataxia Telangiectasia...) :
In ATM deficiency, enhanced
PP2A activity
leads to HDAC4 dephosphorylation and the nuclear accumulation of
HDAC4