Wu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007
(Glioma...) :
LRRC4 down-regulated the expression of phosphorylated ERK2 and up-regulated the expression of total protein JNK2 ( a key molecule of MAPK signaling pathway ) and phosphorylated c-Jun Wu et al., J Cell Physiol 2008
(Glioblastoma...) :
LRRC4 expression significantly inhibited the expression of some cytokines and their receptors determined by microarray and Western blot assays, and dramatically reduced cytokine induced AP-1 , NF-kB, and CyclinD1 activation in glioma cells