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Masuko-Hongo et al., Arthritis Rheum 2004
(Osteoarthritis) :
The specific p38alpha MAPK inhibitor SC906 suppressed IL-1beta induced COX-2 expression but not IL-1beta induced mPGES-1 expression, suggesting preferential involvement of p38beta MAPK in IL-1beta induced mPGES-1 expression
Galán et al., J Hypertens 2011
:
Inhibition of either p38 MAPK ( SB203580 ) or ERK1/2 ( PD98059 ) reduced COX-2 and mPGES-1 expression in cells treated with IL-1ß or the combination of IL-1ß and Ang II