Gene interactions and pathways from curated databases and text-mining

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IRF6 — NPY4R

Text-mined interactions from Literome

Orlicek et al., Shock 1999 : The src family-selective tyrosine kinase inhibitor PP1 blocks LPS and IFN-gamma mediated TNF and iNOS production in murine macrophages
Sunohara et al., J Neurochem 2001 : The Src kinase inhibitor PP2 had no effect, while the closely related inhibitor PP1 actually increased LPS induction of MARCKS and MRP
Napolitani et al., Eur J Immunol 2003 : Inhibition of these kinasesby PP1 uncoupled LPS induced cytokine production from the up-regulation of costimulatory molecules, resulting in DC still capable of stimulating T cell proliferation but much less efficient in inducing Th1 differentiation