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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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NOTCH1 — PDLIM7

Text-mined interactions from Literome

Cotter et al., J Virol 2000 (Cell Transformation, Viral...) : Truncated intracellular NOTCH1 associated with the nuclear membrane ( DeltaE ) transactivates the LMP1 promoter fivefold ; however, the intranucleus localized form of NOTCH1 ( ICN ) transactivates this promoter approximately twofold in chloroamphenicol acetyltransferase (CAT) reporter assays in BJAB cells ... Similarly, another truncated form of NOTCH1 , referred to as ICNW, which contains the tryptophan residue W ( 1767 ) within one of the RBP-Jkappa interacting domains, repressed the LMP1 promoter approximately twofold
Strobl et al., J Virol 2000 (Burkitt Lymphoma) : Northern blot analysis revealed that the LMP2A gene is induced by Notch-IC in the presence of estrogen, whereas increased expression of LMP1 could be detected only if cycloheximide was simultaneously added
Gross et al., Int J Cancer 2011 (Burkitt Lymphoma) : In contrast, NP9 did neither interfere in the activation of the HES1 promoter by Notch nor the induction of the viral LMP1 promoter by EBNA2