◀ Back to RAC1
F2RL2 — RAC1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Nishimura et al., Nat Cell Biol 2005
:
PAR-6-PAR-3 mediates Cdc42 induced
Rac activation through the Rac GEFs STEF/Tiam1 ...
PAR-3 is
required for Cdc42 induced
Rac activation, but is not essential for lamellipodia formation itself
Gopalakrishnan et al., Am J Physiol Cell Physiol 2007
:
ATP depletion reduced
Rac GTPase activity and
induced Par3 , aPKCzeta, and mLgl-1 redistribution from sites of cell-cell contact, which was restored following recovery from ATP depletion
Lee et al., J Neurosci 2013
(Cicatrix) :
NG2 treatment also activates Cdc42, increases the association of Par6 with PKC?, and leads to a
Par3 dependent activation of
Rac1