Gene interactions and pathways from curated databases and text-mining

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FGF7 — MMP14

Text-mined interactions from Literome

Udayakumar et al., Prostate 2004 (Prostatic Neoplasms) : Co-transfection of LNCaP with human MT1-MMP reporter construct and a dominant negative FGFR1 mutant showed that FGF-1 induced MT1-MMP expression in LNCaP cells was completely inhibited by the mutated FGFR-1, indicating that FGF receptor ( FGFR ) activation is necessary for induction of MT1-MMP
Steinberg et al., Development 2005 : FGF7- and FGF10 mediated morphogenesis is inhibited by an MMP inhibitor and a neutralizing antibody to FGF1, suggesting that both FGF1 and MMPs are essential downstream mediators of epithelial morphogenesis
Uitto et al., Am J Pathol 1998 (Gingivitis...) : In these cells, MMP-13 expression at the mRNA and protein level was potently enhanced ( up to sixfold ) by tumor necrosis factor-alpha, transforming growth factor-beta(1), and transforming growth factor-alpha and by keratinocyte growth factor in the presence of heparin