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IL1B — TLR9

Text-mined interactions from Literome

Li et al., J Immunol 2007 : Alum induced IL-1beta and IL-18 production was not due to enhancement of TLR signaling but rather reflected caspase-1 activation and in mouse dendritic cells occurred in a MyD88 independent fashion
Dinarello et al., Immunity 2007 (Inflammation) : Secretion of the proinflammatory cytokine IL-1beta requires caspase-1 and Toll-like receptor ( TLR ) signaling
Kim et al., Immunol Lett 2007 (Arthritis, Rheumatoid...) : TLR stimulation of RA-FLS also induced the production of IL-1beta and TNF-alpha to a lesser extent ; however, it had no effect on IL-17 production ... Inhibition of TLR induced IL-1beta production, which partially reversed the upregulation of RANKL induced by TLR ligands
Ferwerda et al., J Leukoc Biol 2007 (Crohn Disease) : TLR induced TNF-alpha, IL-1beta , and IL-10 production is mediated through MyD88, whereas Toll-IL-1R domain containing adaptor inducing IFN-beta ( TRIF ) promoted the release of IL-1beta
Villacres et al., J Viral Hepat 2008 (Hepatitis C, Chronic) : To a lesser extent, tumour necrosis factor-alpha and IL-1beta responses to TLR stimulation were also compromised
Netea et al., Expert Opin Biol Ther 2008 (Inflammation) : Monocytes can release active IL-1 beta upon stimulation with TLR ligands alone
van de Veerdonk et al., J Infect Dis 2009 (Inflammation) : The transcription of IL-1beta was induced through mannose receptor ( MR ), Toll-like receptor (TLR) 2, and dectin-1 but not through TLR4 and TLR9
Hurst et al., Immunobiology 2009 (Antiphospholipid Syndrome) : Determination of expression-levels using real-time RT-PCR showed significantly augmented TLR dependent IL-1beta and caspase-1 expression
Jung et al., Immunol Lett 2009 (Arthritis, Experimental...) : These data show that TLR2, TLR4 , and TLR6 ligation synergistically stimulates the production of TNF-alpha and IL-1beta in IL-1Ra-deficient mice and suggest that TLRs contribute to the perpetuation of spontaneous arthritis in this animal model
Lamkanfi et al., J Biol Chem 2009 (Inflammation) : IL-1beta secretion further required the Toll-like receptor ( TLR ) adaptors MyD88 and TRIF, and partially relied on TLR2
Kleinnijenhuis et al., Eur J Immunol 2009 : In contrast, TLR4 , TLR9 and TLR1 receptors are not involved in IL-1beta induction
Böni-Schnetzler et al., Endocrinology 2009 : FFA induced IL-1beta and KC expression in mouse islets was completely dependent on the IL-1R/Toll-like receptor ( TLR ) docking protein Myd88 and partly dependent on TLR2 and -4
Mayer-Barber et al., J Immunol 2010 (Tuberculosis, Pulmonary) : Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo