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RAC1 — TBXA2R

Pathways - manually collected, often from reviews:

• NCI Pathway Database Thromboxane A2 receptor signaling: RAC1/GTP complex (RAC1) → TXA2/TP beta complex (TBXA2R) (translocation, inhibits)
  Parent et al., J Biol Chem 1999, Rochdi et al., J Biol Chem 2003, Rochdi et al., J Biol Chem 2004, Laroche et al., J Biol Chem 2005
  Evidence: mutant phenotype
• NCI Pathway Database Thromboxane A2 receptor signaling: RAC1/GTP complex (RAC1) → TXA2/TP beta/beta Arrestin3 complex (TBXA2R-ARR3) (translocation, inhibits)
  Parent et al., J Biol Chem 1999, Rochdi et al., J Biol Chem 2003, Rochdi et al., J Biol Chem 2004, Laroche et al., J Biol Chem 2005
  Evidence: mutant phenotype
• NCI Pathway Database Thromboxane A2 receptor signaling: RAC1/GTP complex (RAC1) → TXA2/TP beta/beta Arrestin2 complex (TBXA2R-ARRB2) (translocation, inhibits)
  Parent et al., J Biol Chem 1999, Rochdi et al., J Biol Chem 2003, Rochdi et al., J Biol Chem 2004, Laroche et al., J Biol Chem 2005, Kelley-Hickie et al., Biochim Biophys Acta 2006
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Thromboxane A2 receptor signaling: RAC1/GTP complex (RAC1) → TXA2/TP beta complex (TBXA2R) (translocation, inhibits)
  Parent et al., J Biol Chem 1999, Rochdi et al., J Biol Chem 2003, Rochdi et al., J Biol Chem 2004, Laroche et al., J Biol Chem 2005, Kelley-Hickie et al., Biochim Biophys Acta 2006
  Evidence: mutant phenotype, physical interaction