Gene interactions and pathways from curated databases and text-mining

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AREG — TNF

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Inatomi et al., Int J Mol Med 2006 : Among the various cytokines and growth factors, interleukin-1beta, tumor necrosis factor-alpha , and EGF strongly induced amphiregulin and epiregulin mRNA expression
Takahashi et al., Indian J Dermatol 2009 : Furthermore, TNF-alpha induced secretion of IL-6, IL-8, EGF, HGF, TGF-alpha, epiregulin, and amphiregulin were compared among these keratinocytes ... The significant induction of TNF-alpha increased IL-6, IL-8, EGF, HGF, TGF-alpha, epiregulin, and amphiregulin , but the increase in these cytokines and growth factors were not different among normal skin, uninvolved, and involved psoriasis