Gene interactions and pathways from curated databases and text-mining

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APC — NOS3

Text-mined interactions from Literome

Hooper et al., Thromb Res 2001 : These data suggest that APC may induce MCP-1 through the inhibition of eNOS
Zhong et al., Anesthesiology 2004 (Myocardial Infarction...) : APC with sevoflurane attenuated NF-kappaB activation and reduced the expression of tumor necrosis factor alpha, interleukin 1, intercellular adhesion molecule 1, and inducible nitric oxide synthase
Franscini et al., Circulation 2004 (Vasculitis) : Endothelial nitric oxide synthase , endothelial adhesion molecule, and vascular cell adhesion molecule-1 were not affected by APC
Baotic et al., Am J Physiol Heart Circ Physiol 2013 (Acute Disease...) : In conclusion, D-4F restored the cardioprotective effect of APC during AHG, possibly by decreasing superoxide generation, which promoted isoflurane induced eNOS signaling and NO biosynthesis