◀ Back to NOS3
APC — NOS3
Text-mined interactions from Literome
Hooper et al., Thromb Res 2001
:
These data suggest that
APC may
induce MCP-1 through the inhibition of
eNOS
Zhong et al., Anesthesiology 2004
(Myocardial Infarction...) :
APC with sevoflurane attenuated NF-kappaB activation and
reduced the expression of tumor necrosis factor alpha, interleukin 1, intercellular adhesion molecule 1, and inducible
nitric oxide synthase
Franscini et al., Circulation 2004
(Vasculitis) :
Endothelial
nitric oxide synthase , endothelial adhesion molecule, and vascular cell adhesion molecule-1 were not
affected by
APC
Baotic et al., Am J Physiol Heart Circ Physiol 2013
(Acute Disease...) :
In conclusion, D-4F restored the cardioprotective effect of
APC during AHG, possibly by decreasing superoxide generation, which
promoted isoflurane induced
eNOS signaling and NO biosynthesis