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CD8A — TSLP
Text-mined interactions from Literome
Akamatsu et al., Clin Exp Immunol 2008
:
Although human TSLP activated DCs induce CD8 ( + ) T-cell proliferation, it is not clear whether
TSLP acts directly on
CD8 ( + ) T cells
Rochman et al., J Immunol 2008
(Lymphopenia) :
We now demonstrate that
CD8 ( + ) T cells express TSLPR and that
TSLP activates both STAT5 and Akt and induces Bcl-2 in these cells ... Correspondingly,
TSLP increases
CD8 ( + ) T cell survival in vitro as well as in wild-type and T-depleted mice in vivo, without altering the homeostatic proliferation of these cells ... Thus, our data reveal that
TSLP contributes to
CD8 ( + ) T cell homeostasis in both normal and lymphopenic conditions
Sugimoto et al., Clin Immunol 2010
:
Thymic stromal lymphopoietin plays an adjuvant role in BCG mediated
CD8 ( + ) cytotoxic T cell responses through dendritic cell activation