Gene interactions and pathways from curated databases and text-mining

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CD8A — TSLP

Text-mined interactions from Literome

Akamatsu et al., Clin Exp Immunol 2008 : Although human TSLP activated DCs induce CD8 ( + ) T-cell proliferation, it is not clear whether TSLP acts directly on CD8 ( + ) T cells
Rochman et al., J Immunol 2008 (Lymphopenia) : We now demonstrate that CD8 ( + ) T cells express TSLPR and that TSLP activates both STAT5 and Akt and induces Bcl-2 in these cells ... Correspondingly, TSLP increases CD8 ( + ) T cell survival in vitro as well as in wild-type and T-depleted mice in vivo, without altering the homeostatic proliferation of these cells ... Thus, our data reveal that TSLP contributes to CD8 ( + ) T cell homeostasis in both normal and lymphopenic conditions
Sugimoto et al., Clin Immunol 2010 : Thymic stromal lymphopoietin plays an adjuvant role in BCG mediated CD8 ( + ) cytotoxic T cell responses through dendritic cell activation