UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CRKL — MET

Pathways - manually collected, often from reviews:

NCI Pathway Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met): CRKL (CRKL) → HGF(dimer)/MET(dimer)/GAB1 complex (MET-GAB1-HGF) (modification, collaborate)
Sakkab et al., J Biol Chem 2000, Posern et al., Oncogene 1998 *
Evidence: physical interaction
NCI Pathway Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met): CRKL (CRKL) → HGF(dimer)/MET(dimer)/GAB1/CRKL complex (MET-GAB1-CRKL-HGF) (modification, collaborate)
Sakkab et al., J Biol Chem 2000, Posern et al., Oncogene 1998 *
Evidence: physical interaction
NCI Pathway Database Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met): HGF(dimer)/MET(dimer)/GAB1 complex (MET-GAB1-HGF) → HGF(dimer)/MET(dimer)/GAB1/CRKL complex (MET-GAB1-CRKL-HGF) (modification, collaborate)
Sakkab et al., J Biol Chem 2000, Posern et al., Oncogene 1998 *
Evidence: physical interaction