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CD14 — SP1
Text-mined interactions from Literome
Koschmieder et al., Int J Oncol 2007
:
In addition, we investigated whether the myeloid transcription factor
Sp1 played a role in decitabine- and VD3 induced
CD14 expression ... Indeed, we found that mithramycin A, a specific inhibitor of Sp1, inhibited both VD3- and decitabine induced upregulation of CD14, which is in line with previous data showing that
Sp1 is
critical for
CD14 promoter activity
Jarvis et al., Infect Immun 1997
:
The transcription factor
Sp1 plays a crucial role in the monocyte-specific expression of
CD14 , a binding site ( or putative receptor ) for lipopolysaccharide (LPS) complexes with LPS binding protein (LBP)